Melatonin mediates seasonal adjustments in immune function
نویسندگان
چکیده
منابع مشابه
Seasonal redistribution of immune function in a migrant shorebird: annual-cycle effects override adjustments to thermal regime.
Throughout the annual cycle, demands on competing physiological systems change, and animals must allocate resources to maximize fitness. Immune function is one such system and is important for survival. Yet detailed empirical data tracking immune function over the entire annual cycle are lacking for most wild animals. We measured constitutive immune indices once a month for a year on captive re...
متن کاملSeasonal immune function and sickness responses.
Winter is a particularly difficult time to breed and survive. Animals monitor day length (photoperiod) to engage seasonally appropriate adaptations in anticipation of harsh winter conditions. I propose that photoperiodic information, mediated by melatonin, might also influence immune responses. Individuals could improve survival if seasonally recurring stressors were anticipated and countered. ...
متن کاملMelatonin receptor subtype MT2 (Mel 1b) and not mt1 (Mel 1a) is associated with melatonin-induced enhancement of cell-mediated and humoral immunity.
Individuals of many vertebrate species undergo seasonal changes in immune function in addition to marked seasonal changes in reproductive, metabolic, and other physiological processes. Despite growing evidence that photoperiod mediates seasonal changes in immunity, little is known regarding the neuroendocrine mechanisms underlying these changes. Enhanced immune function in short days is correla...
متن کاملMelatonin and the seasonal control of reproduction.
Many mammalian species from temperate latitudes exhibit seasonal variations in breeding activity which are controlled by the annual photoperiodic cycle. Photoperiodic information is conveyed through several neural relays from the retina to the pineal gland where the light signal is translated into a daily cycle of melatonin secretion: high at night, low in the day. The length of the nocturnal s...
متن کاملPhotoperiodic adjustments in immune function protect Siberian hamsters from lethal endotoxemia.
Seasonal changes in day length enhance or suppress components of immune function in individuals of several mammalian species. Siberian hamsters (Phodopus sungorus) exhibit multiple changes in neuroendocrine, reproductive, and immune function after exposure to short days. The manner in which these changes are integrated into the host response to pathogens is not well understood. The present expe...
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ژورنال
عنوان ژورنال: Reproduction Nutrition Development
سال: 1999
ISSN: 0926-5287
DOI: 10.1051/rnd:19990310